Wednesday Morning Fun Facts

Fact #1

If some of Fred Flintstone’s neurotransmitters could talk, what would they say? GABA-dabba-doo!

GABA, the endogenously produced inhibitory neurotransmitter which can also be taken in supplemental form, has been shown in animal models of diabetes to reduce obesity, modulate blood glucose levels, improve insulin sensitivity and decrease markers of inflammation through the activation of peripheral GABA receptors.

This implies that GABA could be a new therapy for the treatment of obesity-related Type 2 diabetes and metabolic syndrome.

Source: Oral Treatment with y-Aminobutyric Acid Improves Glucose Tolerance and Insulin Sensitivity by Inhibiting Inflammation in High Fat Diet-Fed Mice

Fact #2

Lung power

Children with severe therapy-resistant asthma (STRA) appear to have poorer lung function and worse symptoms compared to children with moderate asthma, due to lower serum levels of vitamin D, according to the newest research. Lower levels of vitamin D may cause impaired lung function caused by structural changes in the airway muscles of these children, making breathing more difficult.

Source: Relationship between Serum Vitamin D, Disease Severity, and Airway Remodeling in Children with Asthma

Fact #3

How does the brain communicate with the nerves? With a cell phone!

Supplementation of omega-3 fatty acids was shown to confer neuroprotective properties and encourage nerve regeneration in animal models of peripheral nerve injury. The fatty acids, most commonly found in fish oils, were also shown to decreases the severity of muscular atrophy post-injury.

Sources: Improved Outcome after Peripheral Nerve Injury in Mice with Increased Levels of Endogenous Omega-3 Polyunsaturated Fatty Acids

Fact #4

Boomerangst: (n) def:
a morbid feeling of anxiety, apprehension, or insecurity that one is unaccountably about to get whacked in the side of the head by a bent or angular throwing club typically flat on one side and rounded on the other so that it soars or curves in flight.

Magnesium deficiency has been associated with a higher incidence of developing pathological anxiety. Additionally, since magnesium modulates the hypothalamic-pituitary adrenal (HPA) axis, it appears that its deficiency negatively impacts this important aspect of the endocrine system, through which its dysfunction may increase the incidence and severity of anxiety disorders.

Source: Magnesium deficiency induces anxiety and HPA axis dysregulation: Modulation by therapeutic drug treatment

View the product tech sheet for our new NeuroMag™, which features the unique, patented, chelated mineral Magtein™, which is magnesium chelated to threonic acid (magnesium L-threonate). This ionophore has been found to be superior to other forms of magnesium at getting through the blood brain barrier.

Fact #5

Why do brain cells grown in a dish attend the ballet and opera?
Because they are very cultured.

In a recent study, the potent antioxidant alpha lipoic acid displayed properties of neuroprotection in brain cells by increasing the expression of antioxidative genes and phase II detoxification enzymes.

Source: α-Lipoic acid (LA) enantiomers protect SH-SY5Y cells against glutathione depletion


Dr. Demetri Meimaris,  31 Mercer Street, Suite 1A, Hackensack, New Jersey, 07601  (201) 487-3131


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